Glossary

This multilingual glossary provides easy-to-understand definitions for the main scientific terms used on this website in the risk assessment domain. Terms and their definitions are referenced in our communication products as pop-up notes to explain concepts to the public with no specialist knowledge.
Standard English spelling is used throughout. Acronyms are capitalised. Terms are presented in lower case. Entries are translated into all 24 EU official languages.
The glossary is a living document subject to regular updates. Relevant missing terms may be suggested by using the Ask A Question online form.

Disclaimer: Definitions in the glossary are intended solely to help this website's users understand scientific terminology. Definitions may differ from those given in European Union legislation and in the EFSA Journal.

A


An estimate of the amount of a substance in food or drinking water that can be consumed daily over a lifetime without presenting an appreciable risk to health. It is usually expressed as milligrams of the substance per kilogram of body weight per day and applies to chemical substances such as food additives, pesticide residues and veterinary drugs

A substance that acts against harmful organisms, such as pests or diseases, which affect plants

Measures initiated to detect and control animal diseases as early as possible using defined protocols and activities

A one-off or very short term exposure to a substance, usually less than 24 hours

Added sugars are those added to foods during processing, cooking etc., eaten separately, or added to food at the table

A dietary recommendation used when there isn't enough data to calculate an average requirement. An adequate intake is the average nutrient level consumed daily by a typical healthy population that is assumed to be adequate for the population's needs

The acceptable daily intake (ADI) is an estimate of the amount of a substance in food or drinking water that can be consumed daily over a lifetime without presenting an appreciable risk to health. It is usually expressed as milligrams of the substance per kilogram of body weight and applies to chemical substances such as food additives, pesticide residues and veterinary drugs

An abbreviation for "absorption, distribution, metabolism and excretion", the four key processes which describe how drugs and chemicals get into the body, what happens to them while they are there, and how they are eliminated

A change in the health, growth, behaviour or development of an organism that impairs its ability to develop or survive

A method of visualising a chain of events linked by causality that may lead to a harmful outcome for organisms or the environment

The adequate intake (AI) is a dietary recommendation used when there isn't enough data to calculate an Average Requirement. An AI is the average nutrient level consumed daily by a typical healthy population which is assumed to be adequate for the population's needs

related to alleles, which are different versions of a gene found at the same location on a chromosome

A normally harmless substance, such as an ingredient in a foodstuff, that causes an (immediate) allergic reaction in a susceptible person

The ability to trigger an abnormal immune response that leads to an allergic reaction in a person

A method which can be used in research to replace traditional animal testing with non-invasive methods or substitution. See also replacement, reduction and refinement (3Rs)

The constituent block that makes up proteins. Some can be produced by the human body whereas others can be obtained only through the diet

A technique used to make an exact genetic copy of an animal

A method involving animals or animal cells that tests how a substance or diet might cause ill-health in humans

Standardised ways of assessing animal welfare based on animal responses

Describes a substance that acts in opposition to another substance, thus cancelling out its effect; for example, a hormone that, when released in the body, prevents another hormone from working

The ability of microbes to grow in the presence of substances specifically designed to kill them; for example, some human infections are now resistant to antibiotics, raising concerns about their widespread use

A field of science which studies the impact of toxic substances on water life (e.g. fish, crustaceans, aquatic plants and algae)

The average requirement (AR) is the level of a nutrient in the diet that meets the daily needs of half the people in a typical healthy population

comparaison des données brutes et des fichiers associés avec un rapport intermédiaire ou final. La vérification de l'étude a pour but de déterminer l'exactitude de la déclaration des données, de vérifier si les essais ont été effectués conformément au plan de l'étude et aux modes opératoires normalisés, d'obtenir des informations supplémentaires non fournies dans le rapport et d'établir si des pratiques susceptibles de nuire à la validité des données ont été employées. Cet audit est réalisé par les inspecteurs des autorités de vérification des BPL.

The level of a nutrient in the diet that meets the daily needs of half the people in a typical healthy population